Huron County OPP Crime Unit along with Huron-Perth, Elgin-Middlesex, and Oxford-Brant Community Street Crime Units executed a search warrant at a Sills Street home in Seaforth on Friday.
Officers found suspected methamphetamine, fentanyl, and cocaine worth $15,780.
They also recovered cell phones, drug trafficking materials, and cash.
Three people from Seaforth and one from Huron East ranging in ages between 26 and 61 were arrested and charged.
All four were released with February 7th court dates in Goderich.