This afternoon at approximately 12:45pm the Grey Bruce OPP, Bruce County EMS and South Bruce Fire responded to collision involving a car and motorcycle on Berford Street in Wiarton.
The motorcyclist was taken to a London area hospital with serious life-threatening injuries.
The OPP are being assisted by the West Region Traffic Incident Management and Enforcement Team and they remain on the scene.
Berford Street remains closed between William and Jenny Street.